Asst. Prof. Dr. Mohammed Mahmoud Abdulrahman, Associate Dean for Administrative Affairs at the College of Pharmacy, Qortuba University, published a scientific research paper in collaboration with an international research team in the journal Scientific African, published by Elsevier and indexed in Scopus (Q1), Volume 34, 2026.
The research, titled "Artichoke-extract assisted green synthesis of colchicine-decorated ZnO nanoparticles: Characterization, in vitro application and in vivo anti-inflammatory evaluation," focused on developing an innovative nanomedical system using artichoke extract for the green and sustainable synthesis of zinc oxide nanoparticles conjugated with colchicine, aiming to evaluate their anti-inflammatory, antioxidant properties, and potential to reduce liver tissue damage.
Key findings showed free radical scavenging efficacy reaching 76.1%, alongside improved liver function indicators and reduced oxidative stress and inflammation in animal models. Molecular analyses revealed decreased gene expression of pro-inflammatory factors and increased gene expression of the anti-inflammatory cytokine IL-10, highlighting the promising therapeutic potential of the developed nanosystem. This achievement underscores the integration of nanotechnology, molecular pharmacy, and green synthesis, reflecting Qortuba University’s commitment to advancing scientific research, international academic collaboration, and publishing in reputable journals.
Written by: Maryam Mithaq Najm
